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A Prospective Study to Monitor for Tuberculosis During Anti-tumour Necrosis Factor Therapy in Patients With Inflammatory Bowel Disease and Immune-mediated Inflammatory Diseases

May 11, 2018

CK Lee, SH Wong, G Lui,  W Tang,  LS Tam,  M Ip, E Hung,  MH Chen,  JCY Wu, SC Ng


Journal of Crohn's and Colitis


Biologic therapies have revolutionised the treatment of immune-mediated diseases including inflammatory bowel disease [IBD] and rheumatological disorders. However, it is associated with an increased risk of reactivation of latent tuberculosis. In this study, we found that conversion of LTBI is common and occurred early during biologic therapy in an area with intermediate TB burden.


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