From Institute to Community
Crohn’s Disease in Asia is as severe as in the West
Over 30% Patients have Stricturing or Penetrating Disease at Diagnosis
22 December 2015
Crohn’s disease is a subtype of inflammatory bowel disease (IBD). In the past 20 years, its incidence increased 6 times in Hong Kong, from 0.2 per 100,000 persons to nowadays approximately 1.5 per 100,000 persons. CUHK has conducted an epidemiology study in Australia and 8 countries/regions in Asia (China, Hong Kong, Macau, Indonesia, Malaysia, Sri Lanka, Singapore and Thailand), to investigate and follow up new IBD patients. In the past, there has been a perception of a milder disease in Asia than the West. However, this study shown that Crohn’s disease in Asia is as severe as in Australia. Over 30% of patients were diagnosed with stricture and fistula. CUHK found that 47% of new Crohn’s disease patients were treated with immunosuppressants in the first year, while about 10% required biologics. Comparing with initial therapy, there is over 1 fold increase. Cumulative probability of bowel resection at 1 year after diagnosis is 8%, which means it is estimated that 8% of patients require bowel resection within first year of diagnosis. Symptoms that are often overlooked by parents include severe diarrhea, rectal bleeding and underweight. Crohn’s disease is not only life-threatening, it could cause significant physical and emotional distress to patient. Therefore, early diagnosis and treatment of Crohn’s disease is important to control disease activity and maintain quality of life. Support from family and patient group is also important. Have better knowledge is helpful in managing and minimizing Crohn’s disease and symptoms and associated conditions.
TVB Interview about Crohn's disease
9 October, 2015