GG Kaplan and SC Ng, The Lancet Gastroenterology and Hepatology. 12, 2016. 1: p. 307-316. The UK and China provide unique historical perspectives on the evolution of the incidence of infl ammatory bowel disease, which might provide insight into its pathogenesis. During the second half of the 20th century, the incidence of infl ammatory bowel disease rose dramatically in high-income countries. Globalisation at the turn of the 21st century led to rapid economic development of n