Tags

Archive

Our Recent Publications

Gut mucosal virome alterations in ulcerative colitis

T Zuo, SH Wong, K Lam, R Lui, K Cheung, W Tang, JYL Ching, PKS Chan, MCW Chan, JCY Wu, FKL Chan, J Yu, JJY Sung, and SC Ng

Gut

We demonstrated for the first time that UC is characterised by substantial alterations of the mucosa virobiota with functional distortion. Enrichment of Caudovirales bacteriophages, increased phage/bacteria virulence functions and loss of viral-bacterial correlations in the UC mucosa highlight that mucosal virome may play an important role in UC pathogenesis.

Full article: http://dx.doi.org/10.1136/gutjnl-2018-318131

Copyright © 2017. All Rights Reserved. Institute of Digestive Disease, The Chinese University of Hong Kong