Our Recent Publications

Epidemiology of Inflammatory Bowel Disease from 1981 to 2014: Results from a Territory-Wide Populati

SC Ng, WK Leung, HY Shi, MKK Li, CM Leung, CKM Ng, FH Lo, YT Hui, SWC Tsang, YK Chan, CK Loo, KH Chan, AJ Hui, WH Chow, M Harbord, JYL Ching, M Lee, V Chan, W Tang, IFN Hung, J Ho, WC Lao, MTL Wong, SF Sze, EHS Shan, BCY Lam, RWH Tong, LY Mak, SH Wong, JCY Wu, FKL Chan, and JJY Sung, Inflammatory Bowel Diseases. 05, 2016. 22: p. 1954-1960. [IF: 4.525]

Incidence of inflammatory bowel disease (IBD) is increasing in Asia, but population-based prevalence data are limited. We examined IBD incidence and prevalence based on results of a territory-wide IBD registry in Hong Kong. Data on 2575 patients with IBD (1541 ulcerative colitis [UC], 983 Crohn's disease [CD], 51 IBD unclassified) from 1981 to 2014 using hospital and territory-wide administrative coding system were collected. Prevalence and incidence, disease phenotype, surgery, and mortality were analyzed.Adjusted prevalence of IBD, UC, CD, and IBD unclassified per 100,000 individuals in 2014 were 44.0, 24.5, 18.6, and 0.9, respectively. Age-adjusted incidence of IBD per 100,000 individuals increased from 0.10 (95% confidence interval, 0.06-0.16) in 1985 to 3.12 (95% confidence interval, 2.88-3.38) in 2014. UC:CD incidence ratio reduced from 8.9 to 1.0 over 30 years (P < 0.001). In a population-based study in Hong Kong, prevalence of IBD is lower than in the west although comparable to that of other East Asian countries. Complicated CD is common. Overall mortality remains low in Asians with IBD.